Genetics & Genomics
First prion-free cows reported in Nature Biotechnology
Published in Medical Letter on the CDC and FDA, February 4th, 2007
Prion protein is a natural cellular protein that can become misfolded into infectious particles and cause bovine spongiform encephalopathy (BSE, or mad cow disease) and a lethal variant of Creutzfeldt-Jakob disease (vCJD) in humans. Healthy prion protein-free calves should be useful in investigating the function of normal cellular prion protein and the nature of prion diseases. Additionally, the cows should be useful as a source of prion protein-free...
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