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Obesity Therapy

Obecure recruits first patient in Phase II obesity study

Published in Medical Letter on the CDC and FDA, February 25th, 2007

Obecure has commenced its first Phase II clinical trial to evaluate the efficacy of the company's OBE101 drug candidate for weight loss in obese patients.

The study is a double-blinded, placebo-controlled dose-ranging study in about 280 subjects over a period of three months. The study will be carried out at 20 medical sites across the U.S.

Betahistine is currently marketed in many countries for the treatment of vertigo. The drug was first approved in the mid 1960's but was taken off the U.S. market by the U.S. Food & Drug Administration for lack of clinical evidence in that indication. Notably, no safety issues were raised and a recent...

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