Diabetes Immunology
Researchers from University of Rene Descartes describe findings in diabetes immunology
Published in Medical Letter on the CDC and FDA, March 18th, 2007
New research, "Prevention of type 1 diabetes by invariant NKT cells is independent of peripheral CD1d expression," is the subject of a report. According to a study from Paris, France, "Invariant NKT (iNKT) cells can prevent diabetes by inhibiting the differentiation of anti-islet T cells. We recently showed that neither iNKT cell protection against diabetes nor iNKT cell inhibition of T cell differentiation in vitro requires cytokines such as IL-4, IL-10, IL-13, and TGF-beta."
"In contrast, cell-cell contacts were required for iNKT cell inhibition of T cell differentiation in vitro. The present study was designed to determine whether the CD1d molecule is involved in the...
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