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Enterobacteriaceae

Investigators at Health Protection Agency Center for Infections publish new data on Enterobacteriaceae

Published in Medical Letter on the CDC and FDA, June 24th, 2007

Data detailed in "Activity of faropenem against cephalosporin-resistant Enterobacteriaceae" have been presented. According to a study from London, the United Kingdom, "There is a need for new oral agents active against extended-spectrum beta-lactamase (ESBL) producers, as these increasingly cause community-onset infections. We therefore evaluated faropenem, a penem in Phase III development, against recently collected oxyimino-cephalosporin-resistant bacteria."

"We tested 847 consecutive cephalosporin-resistant Enterobacteriaceae collected at 16 centres in South-East U.K. in 2004, 501 of them with CTX-M enzymes; we also tested reference strains and transconjugants...

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