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Diabetes

Safety Concerns Over GlaxoSmithKline's Avandia and Takeda's Actos Open the Door for Rapid Uptake of Merck's Novel Agent Januvia

Published in Medical Letter on the CDC and FDA, July 1st, 2007

Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that recent reports citing safety concerns over GlaxoSmithKline's Avandia and the Food and Drug Administration's decision to add black box warnings about cardiovascular risk to the packaging of Avandia and Takeda's Actos will diminish the dominance of these agents in second-line diabetes therapy. As a result, Merck's Januvia could challenge Avandia and Actos for market share.

The new report Treatment Algorithms in Type 2 Diabetes finds that Avandia and Actos are prescribed to 32.2% of second-line patients, according to patient-level claims...

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