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HIV/AIDS Therapy

Studies from Center for Drug Evaluation and Research provide new data on HIV/AIDS therapy

Published in Medical Letter on the CDC and FDA, July 15th, 2007

Research findings, "Atazanavir-associated nephrolithiasis: cases from the US Food and Drug Administration's Adverse Event Reporting System," are discussed in a new report. "The risk of nephrolithiasis associated with atazanavir is not well characterized. The US Food and Drug Administration's Adverse Event Reporting System was searched for reports of nephrolithiasis in HIV-infected patients taking an atazanavir-based regimen," scientists in the United States report.

"Thirty cases were identified. Many patients required hospitalization for management, including lithotripsy, ureteral stent insertion, or endoscopic stone removal. Some cases of nephrolithiasis resulted in...

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