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Pathology

New data from Department of Agriculture illuminate research in pathology

Published in Medical Letter on the CDC and FDA, September 23rd, 2007

Scientists discuss in "Genetic variation at the tumour virus B locus in commercial and laboratory chicken populations assessed by a medium-throughput or a high-throughput assay" new findings in pathology. "The tumor virus B (TVB) locus encodes cellular receptors mediating infection by three subgroups of avian leukosis virus (B, D, and E). Three major alleles, TVB*S1, TVB*S3, and TVB*R, have been described," researchers in the United States report.

"TVB*S1 encodes a cellular receptor mediating infection of subgroups B, D, and E. TVB*S3 encodes the receptor for two subgroups, B and D, and TVB*R encodes a dysfunctional receptor that does not permit infection by any of the...

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