Neurodegenerative Disease Therapy
Harvard University reports research in neurodegenerative disease therapy
Published in Medical Letter on the CDC and FDA, September 30th, 2007
Current study results from the report, "Nortriptyline delays disease onset in models of chronic neurodegeneration," have been published. "This study was to characterize the neuroprotective effects of nortriptyline, a tricyclic antidepressant, in mouse models of chronic neurodegeneration [amyotrophic lateral sclerosis (ALS) and Huntington's disease (HD)]. Nortriptyline was originally selected from a library screening of 1040 FDA-approved drugs by using isolated mitochondria," scientists writing in the European Journal of Neuroscience report.
"It emerged as a strong inhibitor of mitochondrial permeability transition (mPT). Our results showed that nortriptyline...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Medical Letter on the CDC and FDA
More Articles from Medical Letter on the CDC and FDA
- Adverse Drug Reactions
Study shows adverse drug events reported to the FDA have significantly increased - Cancer Gene Therapy
MIT works toward safer gene therapy - Drug Resistance
Temple Emergency Medicine receives $1.8M to find best MRSA treatment - Epilepsy
A child's IQ could be affected by maternal epilepsy - Internal Medicine
Prescription labels geared toward pharmacies, not patients - Prostate Cancer
Generic prostate drug helps find high-risk cancers early - More from this issue of Medical Letter on the CDC and FDA
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
