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Chromatography

Findings from Jamia Hamdard, Department of Pharmaceutics advance knowledge in chromatography

Published in Medical Letter on the CDC and FDA, December 23rd, 2007

Data detailed in 'Concurrent determination of topotecan and model permeability markers (atenolol, antipyrine, propranolol and furosemide) by reversed phase liquid chromatography: utility in Caco-2 intestinal absorption studies' have been presented. According to recent research published in the Journal of Chromatography B, "A simple, sensitive, specific and high-resolution reversed-phase liquid chromatographic method utilizing ultraviolet detection has been developed and validated for simultaneous determination of topotecan and four intestinal permeability markers (atenolol, antipyrine, propranolol and furosemide) as suggested by US-FDA. Chromatography was carried out on C-18 column...

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