Colon Cancer

Yale University details research in colon cancer

Published in Medical Letter on the CDC and FDA, January 20th, 2008

According to a study from the United States, "Several molecular pathways have been shown to play key roles in the development and progression of colorectal cancer (CRC). This enhanced understanding of tumor biology has provided the rationale for the design and development of novel agents that are directed against important targets, including growth factors, receptors, and tumor-specific/tumor-selective antigens."

"The epidermal growth factor receptor (EGFR) signaling pathway has received much attention over the past 510 years because it is overexpressed in more than 85% of tumors from patients with metastatic CRC. Cetuximab and panitumumab are monoclonal antibodies...

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Source: Medical Letter on the CDC and FDA (2008-01-20)

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