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Data from Norwegian Institute of Public Health, Division of Environmental Medicine advance knowledge in life sciences

Published in Medical Letter on the CDC and FDA, March 23rd, 2008

Data detailed in 'Fluoride-induced IL-8 release in human epithelial lung cells: relationship to EGF-receptor-, SRC- and MAP-kinase activation' have been presented. "Exposure of human epithelial lung cells to fluorides is known to induce a marked increase in the release of interleukin (IL)-8, a chemokine involved in neutrophil recruitment. In the present study, the involvement of mitogen-activating protein kinases (MAPKs), the role of upstream activation of Src family kinases (SFKs), epidermal growth factor receptor (EGFR) activation and the interrelationships between these pathways in fluoride-induced IL-8 were examined in a human epithelial lung cell line (A549)," researchers in Oslo,...

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