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Pancreas

Repligen Initiates Phase 3 Clinical Trial of RG1068 for Pancreatic MRI Imaging

Published in Medical Letter on the CDC and FDA, April 13th, 2008

Repligen Corporation (NASDAQ:RGEN) announced that the Company has initiated a Phase 3 clinical trial to evaluate the use of RG1068, synthetic human secretin, to improve the assessment of pancreatic duct structures by magnetic resonance imaging (MRI). This Phase 3 study is a multi-center, baseline-controlled, single dose study in which approximately 250 patients will receive an unenhanced MRI followed by a secretin-enhanced MRI of the pancreas. This study is designed to assess the sensitivity and specificity of secretin- enhanced MRI to improve the ability to detect pancreatic duct abnormalities relative to MRI alone. Detailed visual assessment of the pancreatic ducts is important in the...

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