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Anthrax Therapy

United States Army Medical Research Institute of Infectious Disease details research in anthrax therapy

Published in Medical Letter on the CDC and FDA, April 20th, 2008

Data detailed in 'Treatment of experimental anthrax with recombinant capsule depolymerase' have been presented. "Bacillus anthracis produces an antiphagocytic gamma-linked poly-D-glutamic acid capsule that is required for virulence. Capsule depolymerase (CapD) is a membrane-associated poly-gamma-glutamate-specific depolymerase encoded on the B. anthracis capsule plasmid, pX02, that is reported to contribute to virulence by anchoring the capsule to the peptidoglycan and partially degrading high-molecular-weight capsule from the bacterial surface," scientists in the United States report.

"We previously demonstrated that treatment with CapD effectively...

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