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Medical Letter on the CDC & FDA

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Leukoplakia



Findings in leukoplakia reported from Emory University, Medical Department



May 18th, 2008

According to a study from the United States, "Oral hairy leukoplakia (OHL) is a common oral manifestation of HIV infection. Clinically, these lesions appear as white plaques on the edges of the tongue."

"Pathophysiologically, these lesions Occur because of infection of oral epithelium with Epstein-Barr virus (EBV). No universally effective therapy exists for OHL. We have previously shown that EBV infection and EBV viral products induce the generation of reactive oxygen. We have also demonstrated that the Food and Drug Administration-approved over-the-counter medication gentian violet is a potent inhibitor of reactive oxygen species. We thus chose to treat a patient with...


Source: Medical Letter on the CDC & FDA (2008-05-18)

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