Medical Letter on the CDC & FDA
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Life Sciences
Research results from V. Vallet and co-authors update knowledge of life sciences
May 18th, 2008
New research, 'Percutaneous penetration and distribution of VX using in vitro pig or human excised skin validation of demeton-S-methyl as adequate simulant for VX skin permeation investigations,' is the subject of a report. According to a study from France, "The organophosphorus (OP) chemical warfare V agent O-ethyl-S-[2(di-isopropylamino)ethyl] methyl phosphonothioate (VX), is a highly toxic compound which mainly penetrates the body via percutaneous pathways. Hence, the following prerequisite: to ascertain compound absorption and percutaneous profile distribution with a view to further assessing the efficacy of topical skin protectants." "We first selected the most...
Source: Medical Letter on the CDC & FDA (2008-05-18)
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