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Diphtheria Vaccines

Researchers from National Institute of Public Health and the Environment detail new studies and findings in the area of diphtheria vaccines

Published in Medical Letter on the CDC and FDA, July 6th, 2008

Research findings, 'Development and validation of a multiplex immunoassay for the simultaneous determination of serum antibodies to Bordetella pertussis, diphtheria and tetanus,' are discussed in a new report. "To increase testing of vaccine induced humoral immunity in immune surveillance studies and vaccine trials, a rapid and simple microsphere-based multiplex assay (pentaplex) was developed for the quantitation of IgG serum antibodies directed against the Bordetella pertussis antigens: Pertussis Toxin (Ptx), Filamentous hemagglutinin (FHA), Pertactin (Prn) and to Diphtheria toxin and Tetanus toxin. All individual antigens were covalently linked to carboxylated microspheres,"...

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