Life Sciences
New life sciences study findings have been reported from University of Idaho
Published in Medical Letter on the CDC and FDA, August 31st, 2008
New investigation results, 'Induction of innate immunity by lipid A mimetics increases survival from pneumonic plague,' are detailed in a study published in Microbiology. "This study analysed the effect of priming the innate immune system using synthetic lipid A mimetics in a Yersinia pestis murine pulmonary infection model. Two aminoalkyl glucosaminide 4-phosphate (AGP) Toll-like receptor 4 (TLR4) ligands, delivered intranasally, extended time to death or protected against a lethal Y. pestis CO92 challenge," investigators in the United States report.
"The level of protection was dependent upon the challenge dose of Y. pestis and the timing of AGP therapy....
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