Anthrax

Reports outline anthrax study findings from West Virginia University

Published in Medical Letter on the CDC and FDA, September 14th, 2008

According to a study from the United States, "A de novo asymmetric approach to the natural product anthrax tetrasaccharide I and an analogue 2 with an anomeric hexyl azide group has been developed from acetylfuran."

"The construction of the tetrasaccharide was achieved by a traditional [3 + 1] glycosylation strategy. An iterative diastereoselective palladium-catalyzed glycosylation, Luche reduction, diastereoselective dihydroxylation, and regioselective acylation were employed for the assembly of the L-rhamno-trisaccharide building block," wrote H.B. Guo and colleagues, West Virginia University.

The researchers concluded: "The anthrose building block...

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Source: Medical Letter on the CDC and FDA (2008-09-14)

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