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UT Southwestern Medical Center

UT Southwestern researchers uncover molecule that keeps pathogens like salmonella in check

Published in Medical Letter on the CDC and FDA, September 21st, 2008

Scientists at UT Southwestern Medical Center have found a potential new way to stop the bacteria that cause gastroenteritis, tularemia and severe diarrhea from making people sick.

The researchers found that the molecule LED209 interferes with the biochemical signals that cause bacteria in our bodies to release toxins.

"What we have here is a completely novel approach to combating illness," said Dr. Vanessa Sperandio, associate professor of microbiology and biochemistry at UT Southwestern and senior author of a study available online today and in a future issue of Science.

Though many antimicrobial drugs are already available, new...

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