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Escherichia Coli
Researchers from University of Edinburgh report on findings in Escherichia coli
November 9th, 2008
"Type III secretion (T3S) from enteric bacteria is a co-ordinated process with a hierarchy of secreted proteins. In enteropathogenic and enterohaemorrhagic Escherichia coli, SepL and SepD are essential for translocator but not effector protein export, but how they function to control this differential secretion is not known," researchers in Scotland report. "This study has focused on the different activities of SepL including membrane localization, SepD binding, EspD export and Tir secretion regulation. Analyses of SepL truncates demonstrated that the different functions associated with SepL can be separated. In particular, SepL with a deletion of 11 amino acids from...
Source: Medical Letter on the CDC & FDA (2008-11-09)
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