Medical Letter on the CDC & FDA
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Life Sciences
Research on life sciences reported by scientists at Texas A&M University
November 9th, 2008
According to a study from the United States, "Inhalational anthrax is initiated by the entry of Bacillus anthracis spores into the lung. A critical early event in the establishment of an infection is the dissemination of spores from the lung." "Using in vitro cell culture assays, we previously demonstrated that B. anthracis spores are capable of entering into epithelial cells of the lung and crossing a barrier of lung epithelial cells without apparent disruption of the barrier integrity, suggesting a novel portal for spores to disseminate from the lung. However, in vivo evidence for spore uptake by epithelial cells has been lacking. Here, using a mouse model, we present...
Source: Medical Letter on the CDC & FDA (2008-11-09)
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