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Lyme Disease
Research on lyme disease detailed by D.A. Jobe and co-authors
November 9th, 2008
According to recent research published in the journal Clinical and Vaccine Immunology, "Highly specific borreliacidal antibodies are induced by infection with Borrelia burgdorferi, and the immunodominant response during early Lyme disease is specific for an epitope within the 7 amino acids nearest the C terminus of OspC. We evaluated the ability of an enzyme-linked immunosorbent assay (ELISA) based on a synthetic peptide (OspC7) that matched the region to detect the response and compared the sensitivity during early Lyme disease to that for an FDA-approved Western blot." "When the optical density value was adjusted to 98% specificity based on the results from...
Source: Medical Letter on the CDC & FDA (2008-11-09)
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