Medical Letter on the CDC & FDA
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Vaccines
New findings from Food & Drug Administration in the area of vaccines published
November 9th, 2008
According to recent research published in the journal Infection and Immunity, "Francisella tularensis, a small gram-negative intracellular bacterium responsible for causing tularemia, is highly pathogenic and classified as a category A agent of bioterrorism. As for other intracellular pathogens, successful protective immune responses to Francisella tularensis require rapid and efficient induction of gamma interferon (IFN-gamma) production." "Studies using intracellular bacteria such as Listeria monocytogenes as well as Francisella suggest that natural killer (NK) and T cells are important sources of IFN-gamma. However, comprehensive characterization of specific...
Source: Medical Letter on the CDC & FDA (2008-11-09)
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