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Flavivirus Therapy
Research reports on flavivirus therapy from H. Malet and colleagues provide new insights
November 9th, 2008
New research, 'The flavivirus polymerase as a target for drug discovery,' is the subject of a report. According to a study from Marseille, France, "Flaviviruses are emerging pathogens of increasingly important public health concern in the world. For most flaviviruses such as dengue virus (DENV) and West Nile virus (WNV) neither vaccine nor antiviral treatment is available." "The viral RNA-dependent RNA polymerase (RdRp) non-structural protein 5 (NS5) has no equivalent in the host cell and is essential for viral replication. Here, we give an overview of the current knowledge regarding Flavivirus RdRp function and structure as it represents an attractive target for drug...
Source: Medical Letter on the CDC & FDA (2008-11-09)
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