Amyotrophic Lateral Sclerosis
Researchers from Food & Drug Administration publish findings in amyotrophic lateral sclerosis
Published in Medical Letter on the CDC and FDA, January 18th, 2009
According to recent research published in the journal Pharmacoepidemiology and Drug Safety, " We detected disproportionate reporting of amyotrophic lateral sclerosis (ALS) with HMG-CoA-reductase inhibitors (statins) in the Food and Drug Administration's (FDA) spontaneous adverse event (AE) reporting system (AERS). To describe the original ALS signal and to provide additional context for interpreting the signal by conducting retrospective analyses of data from long-term, placebo-controlled clinical trials of statins."
" The ALS signal was detected using the multi-item gamma Poisson shrinker(MGPS) algorithm. All AERS cases of ALS reported in association with use...
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