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Molecules help the immune system to detect cells infected with West Nile virus

Published in Medical Letter on the CDC and FDA, March 1st, 2009

New research reveals a model of host-pathogen interaction that explains how the immune system finds and destroys cells infected with a potentially lethal brain virus. The study, published online on February 5th in Immunity, a Cell Press publication, may lead to new treatments for West Nile virus (WNV) and other similar viral infections.

WNV is a single-stranded (ss)RNA virus that is the most common cause of viral inflammation of the brain (encephalitis) in North America, and it has emerged as a significant worldwide public health concern. Infection with the virus, which is spread by mosquitoes, is often asymptomatic but can lead to a potentially fatal inflammation of...

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