Melioidosis

Scientists at Charles Darwin University publish new data on melioidosis

Published in Medical Letter on the CDC and FDA, April 5th, 2009

"Endemic melioidosis is caused by genetically diverse Burkholderia pseudomallei strains. However, clonal outbreaks (multiple cases caused by 1 strain) have occurred, such as from contaminated potable water. B. pseudomallei is designated a group B bioterrorism agent, which necessitates rapidly recognizing point-source outbreaks," scientists in Darwin, Australia report.

"Pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST) can identify genetically related isolates, but results take several days to obtain. We developed a simplified 4-locus multilocus variable number tandem repeat analysis (MLVA-4) for rapid typing and compared results with PFGE and...

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Source: Medical Letter on the CDC and FDA (2009-04-05)

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