Dengue Fever

New findings from Third Military Medical University in the area of dengue fever described

Published in Medical Letter on the CDC and FDA, May 10th, 2009

According to recent research published in the journal Current Microbiology, "Dengue fever and dengue hemorrhagic fever/dengue shock syndrome are highly infectious diseases caused by dengue virus (DV). Specific monoclonal antibodies (mAbs) against DV are vital for diagnosis, pathological studies, and passive immune therapy."

"In this study, purified DV serotype 2 (DV2) was used as antigen and BALB/c mice were immunized to induce specific antibodies. We established five hybridoma cell lines, called 78#, 1E7, 7F7, 8F12, and 8H1, respectively, and evaluated them by enzyme-linked immunosorbent assay, indirect immunofluorescence assay, Western blot, plaque reduction...

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Source: Medical Letter on the CDC and FDA (2009-05-10)

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