Dartmouth College

Two-pronged model could help foil tough cystic fibrosis infections

Published in Medical Letter on the CDC and FDA, May 31st, 2009

Hanover, NH--Dartmouth Medical School researchers have devised a novel approach for thwarting the relentless bacterial infections that thrive in the lungs of people with cystic fibrosis (CF), unlocking new possibilities against a tenacious and toxic hallmark of the common genetic disease.

Combining a mainstay antibiotic with drugs to deprive the bacteria of iron, which facilitates their persistent growth, appears to boost infection killing, they found.

Their research, reported in the American Journal of Respiratory Cell and Molecular Biology online and scheduled for publication, builds on the collaborative expertise of DMS microbiology and lung...

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Source: Medical Letter on the CDC and FDA (2009-05-31)

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