Vaccines

Findings in vaccines reported from J. Huang and co-researchers

Published in Medical Letter on the CDC and FDA, July 12th, 2009

"The potential use of Yersinia pestis as a bioterror agent is a great concern. Development of a stable powder vaccine against Y. pestis and administration of the vaccine by minimally invasive methods could provide an alternative to the traditional liquid formulation and intramuscular injection," scientists in the United States report.

"We evaluated a spray-freeze-dried powder vaccine containing a recombinant F1-V fusion protein of Y. pestis for vaccination against plaque in a mouse model. Mice were immunized with reconstituted spray-freeze-dried F1-V powder via intramuscular injection, microneedle-based intradermal delivery, or noninvasive intranasal administration. By...

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Source: Medical Letter on the CDC and FDA (2009-07-12)

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