Legionnaire Disease Cell Biology
Data on legionnaire disease cell biology detailed by researchers at Tel-Aviv University, George S. Wise Faculty of Life Sciences
Published in Medical Letter on the CDC and FDA, August 2nd, 2009
Current study results from the report, 'A Legionella effector acquired from protozoa is involved in sphingolipids metabolism and is targeted to the host cell mitochondria,' have been published. According to recent research from Israel, "Legionella pneumophila infects alveolar macrophages and protozoa through establishment of an intracellular replication niche. This process is mediated by bacterial effectors translocated into the host cell via the Icm/Dot type IV secretion system."
"Most of the effectors identified so far are unique to L. pneumophila; however, some of the effectors are homologous to eukaryotic proteins. We performed a distribution analysis...
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