Cervical Cancer

Findings from Wuhan University advance knowledge in cervical cancer

Published in Medical Letter on the CDC and FDA, August 9th, 2009

"In previous studies, we firstly isolated a new human papillomavirus type 16 E7 variant (HBE7.16) from cervical cancer biopsies of patients from Wufeng County of Hubei Province, China, where the mortality rate of cervical cancer ranks the highest in China. We identified 2 Mutations in HBE7.16 compared with the prototype E7 gene (E7.16)," researchers in Wuhan, People's Republic of China report.

"The more relevant mutation produces a termination codon, resulting in a truncated E7 protein containing 43 amino acids, making it about half the size of the wild-type. In this study, we investigated the biological function of this HBE7.16 protein. We compared the transforming...

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Source: Medical Letter on the CDC and FDA (2009-08-09)

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