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Research from National Institute of Health Science, Division of Pathology yields new data on life sciences

Published in Medical Letter on the CDC and FDA, August 23rd, 2009

Research findings, 'Limited lactational transfer of acrylamide to rat offspring on maternal oral administration during the gestation and lactation periods,' are discussed in a new report. According to recent research from Setagaya, Japan, "To evaluate the developmental exposure effects of acrylamide (ACR) on the nervous and male reproductive systems, pregnant Sprague-Dawley rats were given ACR at 0, 25, 50 or 100 ppm in the drinking water from gestational day 6 to postnatal day (PND) 21 and histopathological assessment was performed at PND 21. Exposure levels in offspring were examined by measurement of free ACR and hemoglobin (Hb)-ACR adducts on PND 14, and compared with maternal levels...

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