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Headache and Migraine

Data from N.T. Mathew et al provide new insights into headache and migraine

Published in Medical Letter on the CDC and FDA, August 30th, 2009

According to recent research published in the journal Headache, "Objective.- To evaluate efficacy and tolerability of a single, fixed-dose tablet of sumatriptan 85 mg/naproxen sodium 500 mg (sumatriptan/naproxen sodium) vs placebo in migraineurs who had discontinued treatment with a short-acting triptan because of poor response or intolerance. Background.- Triptan monotherapy is ineffective or poorly tolerated in 1 of 3 migraineurs and in 2 of 5 migraine attacks."

"In April, 2008, the Food and Drug Administration approved the combination therapy sumatriptan/naproxen sodium, developed specifically to target multiple migraine mechanisms. This combination product...

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