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Enzyme Research

Research from University of Cincinnati in the area of enzyme research described

Published in Medical Letter on the CDC and FDA, October 11th, 2009

According to a study from the United States, "Currently, the only FDA-approved therapy for acute ischemic stroke is the administration of recombinant tissue plasminogen activator (tPA). Echogenic liposomes (ELIP), phospholipid vesicles filled with gas and fluid, can be manufactured to incorporate tPA. Also. transcranial ultrasound-enhanced thrombolysis can increase the recanalization rate in stroke patients."

"However, there is little data on lytic efficacy of combining ultrasound, echogenic liposomes, and tPA treatment. In this study, we measure the effects of pulsed 120-kHz ultrasound on the lytic efficacy of tPA and tPA-incorporating ELIP (t-ELIP) in an in-vitro...

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