Clinical Trial Research

Research from M.A.C. Kane and co-researchers provides new data on clinical trial research

Published in Medical Letter on the CDC and FDA, December 20th, 2009

"In April, the U. S. Food and Drug Administration approved a new U. S. formulation of botulinum neurotoxin type A (Dysport; Medicis Aesthetics, Inc., Scottsdale, Ariz.). This formulation has demonstrated inhibition of glabellar lines at a 50-unit dose," investigators in the United States report.

"Standard clinical practice is to adjust the dose based on muscle mass. Patients stratified by race/ethnicity were randomized to receive a single treatment of Dysport administered in various doses or placebo. Dysport was administered in a total volume of 0.4 to 0.6 ml for women (50, 60, or 70 units) and 0.5 to 0.7 ml for men (60, 70, or 80 units), based on procerus/corrugator...

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Source: Medical Letter on the CDC and FDA (2009-12-20)

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