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Breast Cancer

Recent studies by M. Martin and co-authors add new data to breast cancer findings

Published in Medical Letter on the CDC and FDA, January 3rd, 2010

According to a study from Madrid, Spain, "Circulating tumor cells (CTCs) can be detected in the peripheral blood of around 50% of patients with metastatic breast cancer. Their numbers are an independent predictor of the patient's progression-free survival (PFS) and of overall survival (OS)."

"However, to date, none of the studies carried out with the most commonly used system of CTC determination (the CellSearch System, approved by the US Food and Drug Administration) has examined the intra-patient variation in CTC numbers, a variation that could impact on prognosis assessment. Experimental design: To evaluate possible circadian variations in the number of CTCs in...

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