Legionnaire Disease Immunology
New research on legionnaire disease immunology from University of Virginia, Department of Medicine summarized
Published in Medical Letter on the CDC and FDA, March 21st, 2010
Investigators publish new data in the report 'Caenorhabditis is a metazoan host for Legionella.' According to recent research from the United States, "We investigated whether nematodes contribute to the persistence, differentiation and amplification of Legionella species in soil, an emerging source for Legionnaires' disease. Here we show that Legionella spp. colonize the intestinal tracts of Caenorhabditis nematodes leading to worm death."
"Susceptibility to Legionella is influenced by innate immune responses governed by the p38 mitogen-activated protein kinase and insulin/insulin growth factor-1 receptor signalling pathways. We also show that L. pneumophila...
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