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Legionnaire Disease

Report summarizes legionnaire disease study findings from Northwestern University

Published in Medical Letter on the CDC and FDA, May 9th, 2010

New investigation results, 'Mediators of lipid A modification, RNA degradation, and central intermediary metabolism facilitate the growth of Legionella pneumophila at low temperatures,' are detailed in a study published in Current Microbiology. "Legionella pneumophila is an aquatic bacterium that is also the agent of Legionnaires' disease pneumonia. Since L. pneumophila is transmitted directly from the environment to the lung, it is important to understand how legionellae survive at low temperatures. To identify genes that are needed for L. pneumophila growth at low temperature, we screened a population of mutagenized legionellae for strains that are...

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