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Molecular Chaperones

Study findings on molecular chaperones are outlined in reports from King's College London, King's College London

Published in Medical Letter on the CDC and FDA, May 16th, 2010

Current study results from the report, 'Cytoskeletal proteins bound to heat-shock protein 70 may elicit resistance to simian immunodeficiency virus infection of CD4(+) T cells,' have been published. According to a study from London, the United Kingdom, "This study is based on the evidence that immunization of macaques with human CD4(+) T cells elicits prevention of simian immunodeficiency virus (SIV) infection. We hypothesized that heat-shock protein 70 (HSP70) isolated from CD4(+) T cells may act as a chaperone and carry the protective host proteins."

"Two moieties of HSP70 were affinity-purified from human CD4(+) T cells; an ADP preparation with HSP70-bound proteins...

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