Cancer Vaccines

New cancer vaccines research from Sichuan University outlined

Published in Medical Letter on the CDC and FDA, May 16th, 2010

"Immunization with xenogeneic antigens is an attractive approach to induce cross-reactive humoral and cellular immunity to inhibit tumor growth or angiogenesis. To identify novel xenogenic targets for immunotherapy, we have developed a modified serological expression cloning (SEREX) strategy, termed Cross-reactive SEREX (CR-SEREX)," researchers in Chengdu, People's Republic of China report.

"Among 78 positive clones identified by CR-SEREX, Xenopus receptor for hyaluronic-acid-mediated motility (xRHAMM) was most frequently identified (18 times), indicating the strongest immunogenic potential for xenogenic immunotherapy. A DNA vaccine based on xRHAMM effectively induced a...

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Source: Medical Letter on the CDC and FDA (2010-05-16)

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