Respiratory Syncytial Viruses

New respiratory syncytial viruses study findings have been reported from Oregon State University

Published in Medical Letter on the CDC and FDA, May 16th, 2010

According to recent research from the United States, "Human Respiratory Syncytial Virus (HRSV) is an important pathogen and is associated with mortality in the young, old, and immuno-compromised. Due to the lack of effective therapeutic antivirals or a vaccine, there is a critical need for continued research in this field."

"Here we tested the ability of the FDA approved proteasome inhibitor bortezomib to inhibit HRSV in vitro and in vivo. We observed significant inhibition of HRSV replication in Vero cells at bortezomib concentrations from 20 to 40 ng/ml. Bortezomib was well tolerated in mice when administered intranasally at concentrations of <= 03 mg/kg or...

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Source: Medical Letter on the CDC and FDA (2010-05-16)

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