Mycobacterium tuberculosis
Reports from Statens Serum Institute, Department of Infectious Disease describe recent advances in Mycobacterium tuberculosis
Published in Medical Letter on the CDC and FDA, May 30th, 2010
A new study, 'Difference in TB10.4 T-cell epitope recognition following immunization with recombinant TB10.4, BCG or infection with Mycobacterium tuberculosis,' is now available. "Most novel vaccines against infectious diseases are based on recombinant Ag; however, only few studies have compared Ag-specific immune responses induced by natural infection with that induced by the same Ag in a recombinant form. Here, we studied the epitope recognition pattern of the tuberculosis vaccine Ag, TB10.4, in a recombinant form, or when expressed by the pathogen Mycobacterium tuberculosis (M.tb), or by the current anti-tuberculosis vaccine, Mycobacterium bovis BCG," scientists writing in...
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