Lung Cancer

Research data from Northeastern University update understanding of lung cancer

Published in Medical Letter on the CDC and FDA, June 6th, 2010

"A mass spectrometric (MS)-based strategy for antigen (Ag) identification and characterization of globally produced monoclonal antibodies (mAbs) is described. Mice were immunized with a mixture of native glycoproteins, isolated from the pooled plasma of patients with nonsmall cell lung cancer (NSCLC), to generate a library of IgG-secreting hybridomas," scientists in the United States report.

"Prior to immunization, the pooled NSCLC plasma was subjected to 3-sequential steps of affinity fractionation, including high abundant plasma protein depletion, glycoprotein enrichment, and polyclonal antibody affinity chromatography normalization. In this paper, to demonstrate the...

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Source: Medical Letter on the CDC and FDA (2010-06-06)

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