Research from Virginia Commonwealth University, Institute of Molecular Medicine has provided new data on biological products

Researchers detail in 'Superior antitumor response induced by large stress protein chaperoned protein antigen compared with peptide antigen,' new data in biological products. According to a study from the United States, "Our previous studies have demonstrated that the natural chaperone complexes of full-length tumor protein Ags (e.g., gp100) and large stress proteins (e.g., hsp110 and grp170) with exceptional Ag-holding capabilities augment potent tumor protective immunity. In this study, we assess the peptide-interacting property of these large chaperones and, for the first time, compare the immunogenicity of the recombinant chaperone vaccines targeting two forms of Ags (protein versus...

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