Published in Medical Letter on the CDC and FDA, February 27th, 2011
"We have identified the amino acid sites that are related to the host species-specific adaptations by systematically comparing the evolutionary dynamics of HA1 between human and avian hosts for both H1N1 and H3N2 viruses. We can thus refine the ''positively selected sites'' in the HA1 domain of these two virus subtypes to those that occur only in humans. We further demonstrate that the...
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