Bacterial Vaccines
Recent Findings in Bacterial Vaccines Described by Researchers from Center for Biologics Evaluation and Research
Published in Medical Letter on the CDC and FDA, March 20th, 2011
2011 MAR 20 -- Investigators publish new data in the report 'Suppressive effect of bacterial polysaccharides on BAFF system is responsible for their poor immunogenicity.' "Capsular polysaccharides of encapsulated bacteria are weakly immunogenic T cell-independent type 2 (TI-2) Ags. Recent findings suggest that BAFF system molecules have a critical role in the development of Ab responses against TI-2 Ags," scientists writing in the Journal of Immunology report.
"In this study, we investigated the effect of bacterial polysaccharides on B cell responses to BAFF and a proliferation-inducing ligand (APRIL). We determined that B cells exposed to...
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