HIV/AIDS

New Findings from Albert Einstein College of Medicine in the Area of HIV/AIDS Published

Published in Medical Letter on the CDC and FDA, June 26th, 2011

2011 JUN 26 -- According to recent research from Bronx, United States, "Ebola virus (EboV) and Marburg virus (MarV) (filoviruses) are the causative agents of severe hemorrhagic fever. Infection begins with uptake of particles into cellular endosomes, where the viral envelope glycoprotein (GP) catalyzes fusion between the viral and host cell membranes."

"This fusion event is thought to involve conformational rearrangements of the transmembrane subunit (GP2) of the envelope spike that ultimately result in formation of a six-helix bundle by the N- and C-terminal heptad repeat (NHR and CHR, respectively) regions of GP2. Infection by other viruses employing...

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Source: Medical Letter on the CDC and FDA (2011-06-26)

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