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Immunization

New Immunization Data Have Been Reported by J.S. Hansen and Co-Authors

Published in Medical Letter on the CDC and FDA, June 26th, 2011

2011 JUN 26 -- "The prevalence of allergic diseases is influenced by sex and age. Although mouse models are widely used in allergy research, few experimental studies have examined the interaction effects of sex and age on allergy outcomes," investigators in Oslo, Norway report.

"Our aim was to investigate the individual and combined effects of sex and age on allergic sensitization and inflammation in two mouse models: an intraperitoneal (i.p.) and an intranasal (i.n.) sensitization model. We also investigated how the allergen immunization dose interacted with age and sex in the i.p. model. Female and male mice were immunized i.p. or i.n. with ovalbumin when...

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