Influenza A Virus Subtype H1N1
Findings from Sapienza University of Rome Advance Knowledge in Influenza A Virus Subtype H1N1
Published in Medical Letter on the CDC and FDA, July 31st, 2011
"To better understand the pathogenic characteristics of the pandemic 2009 H1N1 influenza virus (pH1N1) from an innate immunity viewpoint, we investigated whether in vitro pH1N1 is sensitive to the antiviral activity of IFN beta, leukocyte IFN alpha, and several IFN alpha subtypes in a human lung adenocarcinoma epithelial cell line under single-growth cycle conditions. The results showed that 50% inhibitory concentration values against pH1N1 for various type I IFN preparations were higher than those against the...
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